• Catherine L Lawson, Rutgers University, Director
• Helen M Berman, Rutgers University
• Brinda Vallat, Rutgers University
• Li Chen, Rutgers University
• Craig L Zirbel, Bowling Green State University
• Neocles B Leontis, Bowling Green State University (deceased)

• Helen M Berman, Rutgers University
• Wilma K Olson, Rutgers University
• David Beveridge, Wesleyan University

The Nucleic Acid Database (NDB) Project was founded in 1992, with the goal of archiving and distributing structural information about nucleic acids. The Nucleic Acid Knowledge Base (NAKB) is being developed as the planned successor to NDB. NDB/NAKB are funded by the National Institutes of Health R01 GM085328. NDB has been funded by National Science Foundation and the Department of Energy in the past.

NAKB/NDB are located at Rutgers University in the Institute for Quantitative Biomedicine, 174 Frelinghuysen Rd, Piscataway, NJ USA, 08854-8076

Researchers who use the NDB should cite:

• Berman HM, Olson WK, Beveridge DL, Westbrook J, Gelbin A, Demeny T, Hsieh SH, Srinivasan AR, Schneider B (1992) The Nucleic Acid Database: A Comprehensive Relational Database of Three-Dimensional Structures of Nucleic Acids. Biophys. J. 63, 751-759. DOI
• Coimbatore Narayanan B, Westbrook J, Ghosh S, Petrov AI, Sweeney B, Zirbel CL, Leontis NB, Berman HM (2014) The Nucleic Acid Database: new features and capabilities. Nucleic Acids Res 42, D114-22. DOI

The history of NDB and plan for NAKB are described here:

• Berman HM, Lawson CL, Schneider B (2022) Developing Community Resources for Nucleic Acid Structures. Life 12, 540. DOI

Please send questions, comments, suggestions about NAKB to help@nakb.org.

NAKB is currently updated weekly on Thursdays, ~noon US ET (timing may change in future). Current update info is shown in the banner at the top of every page.

Resource	Update Frequency	Version
NAKB Annotations	weekly	banner date
RCSB PDB (API)	weekly	banner date
Representative RNA Structure Sets	weekly	banner version
DNATCO	weekly	banner date
ONQUADRO	weekly	banner date
G4DSSR		2023-07-31
RNACentral	semiannual	v22 2023-02-23
Rfam	semiannual	v14.9 2022-11-15
3D FootPrint	semiannual	2023-06-17
DNAproDB		2023-06-14
PANTHER Protein Classes		v17.0 2022-02-23

NAKB Feature(s)		Software
2D fold diagrams		RNAview v.1.0
NA parameter tables, annotations		X3DNA-DSSR v.2.4
NA and Protein Sequence Clusters		CD-HIT, CD-HIT-ESTv.4.8.1
template-based 2D fold viewer		R2DTv.1.3
3D visualization		Mol*